Фармакология и фармацевтика

Производство иных белков медицинского назначения

- гормонов (например, эритропоэтин, гормон роста – соматотропин); erythropoietin, also known as erythropoetin or erthropoyetin or EPO, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. It is a cytokine (protein signaling molecule) for erythrocyte (red blood cell) precursors in the bone marrow.

- интерферонов; interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.

- белков-переносчиков лекарственных веществ

Пример: с помощью бакуловирусов – вирусов, поражающих насекомых (чешуекрылые, двукрылые и перепончатокрылые), в клетки насекомых, поддерживаемые в культуре, были введены и экспрессированы чужеродные гены. Удалось получить следующие рекомбинантные белки: альфа- и бета- интерферон, антиген вируса лихорадки денге, эритропоэтин, интерлейкин-2, белок-переносчик лекарственных веществ.

Определение фармакологии. Pharmacology is the branch of medicine and biology concerned with the study of drug action, where a drug can be broadly defined as any man-made, natural, or endogenous (within the cell) molecule which exerts a biochemical and/or physiological effect on the cell, tissue, organ, or organism. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, interactions, toxicology, therapy, and medical applications and antipathogenic capabilities. The two main areas of pharmacology are pharmacodynamics and pharmacokinetics.

Pharmaceutics is the discipline of pharmacy that deals with the process of turning a new chemical entity (NCE) into a medication to be used safely and effectively by patients. It is also called the science of dosage form design. There are many chemicals with pharmacological properties, but need special measures to help them achieve therapeutically relevant amounts at their sites of action. Pharmaceutics helps relate the formulation of drugs to their delivery and disposition in the body.

Дата добавления: 2013-12-12