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Rules of distribution of medicine




Factors Affecting Medication Response

Misuse of Medications and Risks

When prescribed and taken appropriately, drugs have many benefits: They treat diseases and infections, help manage symptoms of chronic conditions, and can contribute to an improved quality of life. But medicines can also cause problems.

High blood pressure, for example, is often treated with several different drugs. Many older people have multiple cardiovascular risk factors--high blood pressure, diabetes, abnormal cholesterol--and will often need multiple drugs to treat them. Unless supervised by a doctor, however, taking a mixture of drugs can be dangerous. For example, a person who takes a blood-thinning medication should not take it with aspirin, which will thin the blood even more. And antacids can interfere with absorption of certain drugs for Parkinson's disease, high blood pressure, and heart disease. Before prescribing any new drug to an older patient, a doctor should be aware of all the other drugs the patient may be taking.

Another example are heparin and warfarin. These are medications whose use or misuse carry ignificant potential for injury.

Subtherapeutic levels can lead to thromboembolic complications in patients with atrial fibrillation or deep venous thrombosis, while supratherapeutic levels can lead to bleeding complications.

These medications are commonly involved in adverse drug events for a variety of reasons, including the complexity of dosing and monitoring, patient compliance, numerous drug interactions, and dietary interactions that can affect drug levels. Strategies to improve both the dosing and monitoring of these high-risk drugs have potential to reduce the associated risks of bleeding or thromboembolic events.

Age

Weight

Gender

Ethnic background

Physical health

Psychological status

Environmental temperature

Amount of food in stomach

Dosage form

Use the rule of 5 R!

 

The “Five Cs/Rs”:

· Correct/Right Patient/Child

· Correct/Right Medicine

· Correct/Right Dose

· Correct/Right Time

· Correct/Right Route

Check exp. date, name, dosage, doctors prescription, evaluate its looks, give to the patient, mark in the list of prescriptions, put the signature.

Per os medicine should been taken under the nurse supervision.

Applying of narcotic medicine only in doctor presence, history case marks, list of prescriptions, journal of narcotic medicine account.

"Before food" - 15-30 min. "After food" - 15-30 min. On an empty stomach (vermicide, purgative) in the morning. Somnolent – 30 min before sleep.

Nurse should told about side effects.

Tablets that don’t have divide line cant been divided.

Not possible:

Keep medicine with disinfectant solutions.

Distribute medicine without prescription, make changes, put pills into the boxes preliminary, change or put away from drug store package.

 

The administration of a medicine is a common but important clinical procedure. It is the manner in which a medicine is administered that will determine to some extent whether or not the patient gains any clinical benefit, and whether they suffer any adverse effect from their medicines. For example, intravenous furosemide administered too quickly can cause deafness; oral penicillin given with food will not be well absorbed; over-application of topical steroids will cause thinning of the skin and may lead to systemic side-effects.

 

Two main factors determine whether or not a drug will reach its intended site of action in the body:

The bioavailability of the drug;

How the drug is given (route of administration).




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