This Drug Should Not Be Taken If. Possible Advantages of This Drug

Possible Advantages of This Drug

Available Dosage Forms and Strengths

OMEPRAZOLE

TEXT 7. Read the following text and say how this drug works.

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Introduced: 1986

Prescription: USA: Yes Canada: Yes

Available as Generic: USA: No Canada: No

Brand Name: Prilosec (formerly Losec)

Class: Antiulcer, gastric acid inhibitor

Controlled Drug: USA: No

Canada: No

Principal Uses

As a Single Drug Product: Used primarily to inhibit the secretion of stomach acid, an important first step in the treatment of several conditions associated with excessive stomach acid production: acute and chronic gastritis, reflux esophagitis, Zollinger-Ellison syndrome, mastocytosis, endocrine adenomas, active gastric and duodenal ulcer.

How This Drug Works: By inhibiting the action of a specific enzyme system in the acid-secreting cells of the stomach lining, this drug arrests the production of stomach acid and thereby (1) eliminates a principal cause of the condition under treatment, and (2) creates an environment conducive to healing.

Capsules, delayed-release — 20 mg

Usual Adult Dosage Range: Reflux esophagitis: 20 mg to 40 mg once daily

for 4 to 8 weeks.

Excessive stomach acid conditions: 60 mg once daily for as long as neces­sary.

Gastric and duodenal ulcer: 20 mg to 40 mg once daily for 4 to 8 weeks.

In extreme conditions, doses of 120 mg daily, in divided doses, have been used. Note: Actual dosage and administration schedule must be determined by the physician for each patient individually.

Dosing Instructions: Take immediately before eating, preferably the morn­ing meal. The capsule should be swallowed whole without opening; the contents should not be crushed or chewed. This drug may be taken concurrently with antacids if they are needed to relieve stomach pain.

Usual Duration of Use:

Continual use on a regular schedule for 2 to 3 weeks is usually necessary to determine this drug's effectiveness in suppressing stomach acid pro­duction. Long-term use (months to years) requires periodic evaluation of response and dosage adjustment. Consult your physician on a regu­lar basis.

Effectively inhibits acid secretion at all times: basal conditions (stomach empty and at rest) and following food, alcohol, smoking or other stimulants.

Is more effective than H-2 receptor blocking drugs in treating severe reflux esophagitis and refractory duodenal ulcer.

Currently a "Drug of Choice"

for the short-term treatment of severe reflux esophagitis and for the long-term treatment of Zollinger-EUison syndrome.

• you have had an allergic reaction to it previously.

• you have a currently active bone marrow or blood cell disorder.

Дата добавления: 2015-06-25