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Available Dosage Forms and Strengths




Principal Uses

ASPIRIN

TEXT 2. Read the following text and translate it into Ukrainian using a dictionary.

(AS pir in)

Other Names: ASA, acetylsalicylic acid

Introduced: 1899

Prescription: USA: No Canada: No

Available as Generic: Yes

Class: Mild analgesic, anti-inflammatory, antiplatelet, antipyretic, salicylates

Controlled Drug: USA: No Canada: No

 

Brand Names: Alka-Seltzer Effervescent Pain Reliever & Antacid [CD], Alka-Seltzer Plus [CD], ♦Aspirin*, Bayer Aspirin, Bayer Children's Chewable As­pirin, Bufferin [CD], Bufferin w/Codeine [CD], 4-Way Cold Tablets [CD], ♦Oxycodan [CD], Percodan [CDTrigesic [CD]

As a Single Drug Product: To relieve mild to moderate pain from any cause, to provide symptomatic relief in conditions characterized by inflammation and to reduce high fever. A major use is to treat musculoskeletal disorders, especially acute and chronic arthritis. It is also used selectively in low dosage to prevent platelet embolism to the brain (in men) and to reduce the risk of thromboembolism in patients recovering from a recent heart attack, in those with artificial heart valves and in those undergoing hip surgery.

As a Combination Drug Product [CD]: Frequently combined with other mild or strong analgesic drugs to enhance pain relief. Also combined with antihistamines and decongestants in many cold preparations to relieve the headache and general discomfort that often accompany respiratory infections.

How This Drug Works: Aspirin reduces the tissue concentrations of prosta­glandins, chemicals involved in the production of inflammation and pain. By modifying the temperature-regulating center in the brain, dilating blood vessels in the skin, and increasing sweating, aspirin hastens the loss of body heat and reduces fever. By preventing the production of thromboxane in blood platelets, aspirin inhibits the aggregation of platelets and the initiation of blood clots.

Capsules, enteric-coated — 500 mg Capsules, enteric-coated granules — 325 mg

Gum tablets — 227.5 mg

Suppositories — 60 mg, 120 mg, 125 mg, 130 mg, 195 mg, 200 mg, 300 mg, 325 mg, 600 mg, 650 mg, 1.2 grams Tablets — 65 mg, 81 mg, 325 mg, 500 mg Tablets, chewable — 81 mg

Tablets, enteric-coated — 325 mg, 500 mg, 650 mg, 975 mg Tablets, prolonged-action — 650 mg, 800 mg

Usual Adult Dosage Range: For pain or fever—325 to 650 mg/4 hours as needed. For arthritis (and related conditions)—3600 to 5400 mg daily

80 to 150 mg/24 to 48 hours. Note: For long-term use, actual dosage and administration schedule must be determined by the physician for each patient individually.

Dosing Instructions: Take with food, milk, or a full glass of water to reduce

stomach irritation. Regular tablets may be crushed and capsules opened for administration. Enteric-coated tablets, prolonged-action tablets, A.S.A. Enseals, Cama tablets and Ecotrin tablets should not be crushed.

Usual Duration of Use: Short-term use is recommended—3 to 5 days. Daily use should not exceed 10 days without physician supervision. Continual use on a regular schedule for 1 week is usually necessary to determine this drug's effectiveness in relieving the symptoms of chronic arthritis. Long-term use requires periodic evaluation of response and dosage adjustment. Consult your physician on a regular basis.




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