Advisability of Use During Pregnancy. 1. It is most important to understand that aspirin is a drug

Precautions for Use

CAUTION

1. It is most important to understand that aspirin is a drug. While it is
one of our most useful drugs, we have an unrealistic sense of safety
and unconcern regarding its action within the body and its potential
for adverse effects.

2. In order to know if you are taking aspirin, make it a point to learn the contents of all drugs you take—those prescribed by your physician and those you purchase over-the-counter (OTC) without prescription.

3. Limit the dose of aspirin to no more than 3 tablets (975 mg) at one time, allow at least 4 hours between doses and take no more than 10 tablets (3250 mg) in 24 hours without physician supervision.

4. Remember that aspirin can

· cause new illnesses.

· complicate existing illnesses.

· complicate pregnancy.

· complicate surgery.

· interact unfavorably with other drugs.

5. When your physician asks "Are you taking any drugs?" the answer is yes if you are taking aspirin. This also applies to any nonprescription drug you may be taking.

By Infants and Children: Reye syndrome (brain and liver damage in children, often fatal) can follow flu or chicken pox in children and teenagers. While the exact cause and nature of the syndrome are not known, some reports suggest that the use of aspirin by children with flu or chicken pox can increase the risk of developing this complication. Consult your physician before giving aspirin to a child or teenager with chicken pox, flu or similar infection.

Usual dosage schedule for children:

Up to 2 years of age—consult physician.

2 to 4 years of age—160 mg/4 hours, up to 5 doses/24 hours.

4 to 6 years of age—240 mg/4 hours, up to 5 doses/24 hours.

6 to 9 years of age—320 mg/4 hours, up to 5 doses/24 hours.

9 to 11 years of age—400 mg/4 hours, up to 5 doses/24 hours.

11 to 12 years of age—480 mg/4 hours, up to 5 doses/24 hours.

Do not exceed 5 days of continual use without consulting your physician.

Give all doses with food, milk or a full glass of water.

By Those over 60 Years of Age: The natural decline in kidney function can reduce your tolerance for aspirin. Observe for indications of excessive dosage: nervous irritabilty, confusion, ringing in the ears, deafness, loss of appetite, nausea and stomach irritation. Aspirin can cause excessive bleeding from the stomach in sensitive individuals. This can occur as "silent" bleeding of small amounts over an extended period of time, resulting in anemia. In addition, sudden hemorrhage can occur, even without a history of stomach ulcer. Observe stools for gray to black discoloration—an indication of stomach bleeding.

Pregnancy Category: D (tentative). See Pregnancy Code inside back cover. Animal studies: Significant birth defects due to this drug have been reported.

Human studies: Information from studies of pregnant women indicates no increased risk of birth defects in 32,164 pregnancies exposed to aspirin. However, studies show that the regular use of salicylates dur­ing pregnancy is often detrimental to the health of the mother and to the welfare of the fetus. Excessive use of salicylate drugs can cause anemia, hemorrhage before and after delivery and an increased incidence of stillbirths and newborn deaths. It is advisable to limit the use of aspirin during pregnancy to small doses and for brief periods of time, and to avoid aspirin altogether during the last 3 months.

Дата добавления: 2015-06-25