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If any of the following develop, consult your physician promptly for guidance




Inform Your Physician Before Taking This Drug If

This Drug Should Not Be Taken If

Available Dosage Forms and Strengths

Principal Uses

MINOCYCLINE

TEXT 10. Read the following text attentively and choose the sentences containing the word “diarrhea”. Translate them in writing.

(min oh SI kleen)

Introduced: 1970

Class: Antibiotic, tetracyclines

Prescription: USA: Yes

Controlled Drug: USA: No Canada: Yes

Available as Generic: Yes

Brand Name: Minocin

As a Single Drug Product: This member of the tetracycline drug class is used primarily to treat (1) a broad range of infections caused by susceptible bacteria and protozoa, and (2) severe, resistant pustular acne.

How This Drug Works: This drug prevents the growth and multiplication of susceptible bacteria by interfering with their formation of essential proteins.

Capsules — 50 mg, 100 mg Capsules,

prolonged-action (Minocin) — 50 mg, 100 mg

Oral suspension — 50 mg per 5-ml teaspoonful (5% alcohol)

Tablets, film-coated — 50 mg, 100 mg

Usual Adult Dosage Range: Initially, 200 mg; then 100 mg/12 hours or 50

mg/6 hours. The total daily dosage should not exceed 350 mg the first day or 200 mg thereafter. Note: Actual dosage and administration schedule must be determined by the physician for each patient individually.

Dosing Instructions: May be taken without regard to food. Take at same

time each day, with a full glass of water or milk. Take the full course prescribed. The tablet may be crushed and the capsule may be opened for administration. However, the pellets in Minocin capsules should not be chewed or crushed; mix with soft food and swallow unaltered.

Usual Duration of Use: The time required to control the infection and be free of fever and symptoms for 48 hours. This varies with the nature of the infection.

• you are allergic to any tetracycline drug (see Drug Class, Section Four).

• you are pregnant or breast-feeding.

• it is prescribed for a child under 8 years of age.

• you have a history of liver or kidney disease.

• you have systemic lupus erythematosus.

• you are taking any penicillin drug.

• you are taking any anticoagulant drug.

• you plan to have surgery under general anesthesia in the near future.

Possible Side-Effects (natural, expected and unavoidable drug actions) Superinfections, often due to yeast organisms. These can occur in the mouth, intestinal tract, rectum and/or vagina, resulting in rectal and vaginal itching.

Possible Adverse Effects (unusual, unexpected and infrequent reactions)

Mild Adverse Effects Allergic Reactions: Skin rash, hives, itching of hands and feet, swelling

of face or extremities. Marked dizziness, unsteadiness, incoordination (usually occurs during

the first 3 days). Pigmentation of skin.

Loss of appetite, stomach irritation, nausea, vomiting, diarrhea. Irritation of mouth or tongue, "black tongue," sore throat, abdominal

cramping or pain. Serious Adverse Effects Allergic Reactions: Anaphylactic reaction, asthma, fever,

swollen joints, abnormal bleeding or bruising. Permanent discoloration and/or malformation of teeth when taken

under 8 years of age, including unborn child and infant.

Possible Effects on Sexual Function: None reported.




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