Possible Effects on Laboratory Tests. Natural Diseases or Disorders That May Be Activated by This Drug

Natural Diseases or Disorders That May Be Activated by This Drug

Adverse Effects That May Mimic Natural Diseases or Disorders

Possible Effects on Sexual Function

Possible Adverse Effects(unusual, unexpected and infrequent reactions) If any of the following develop, consult your physicianpromptly for guidance.

Inform Your Physician Before Taking This Drug If

This Drug Should Not Be Taken If

• you have had an allergic reaction to it previously.

• you are subject to asthma or nasal polyps caused by aspirin.

• you are pregnant or breast-feeding.

• you have active peptic ulcer disease or any form of gastrointestinal
ulceration or bleeding.

• you have a bleeding disorder or a blood cell disorder.

• you have severe impairment of kidney function.

• you are allergic to aspirin or to other aspirin substitutes.

• you have a history of peptic ulcer disease, Crohn's disease, ulcerative
colitis or any type of bleeding disorder.

• you have a history of epilepsy, Parkinson's disease or mental illness
(psychosis).

• you have impaired liver or kidney function.

• you have high blood pressure or a history of heart failure.

• you are taking any of the following: acetaminophen, aspirin or other
aspirin substitutes, anticoagulants, oral antidiabetic drugs.

Possible Side-Effects (natural, expected and unavoidable drug actions) Drowsiness, ringing in ears, fluid retention.

Mild Adverse Effects

Allergic Reactions: Skin rash, hives, itching, localized swellings of face and/or extremities.

Headache, dizziness, feelings of detachment.

Mouth sores, indigestion, nausea, vomiting, diarrhea.

Temporary loss of hair. Serious Adverse Effects

Allergic Reactions: Asthma, difficult breathing, mouth irritation.

Blurred vision, confusion, depression.

Active peptic ulcer, with or without bleeding.

Liver damage with jaundice.

Kidney damage with painful urination, bloody urine, reduced urine for­mation.

Rare bone marrow depression - fatigue, weakness, fever, sore throat, abnormal bleeding or bruising.

Peripheral neuritis.

Enlargement and tenderness of both male and female breasts. Nonmenstrual vaginal bleeding.

Possible Delayed Adverse Effects: Mild anemia due to "silent" blood loss from the stomach (less than that caused by aspirin).

Liver reaction may suggest viral hepatitis.

Peptic ulcer disease, ulcerative colitis.

Complete blood cell counts: decreased red cells, hemoglobin, white cells and platelets.

Prothrombin time: increased.

Blood lithium level: increased.

Liver function tests: increased liver enzymes (ALT/GPT, AST/GOT and

alkaline phosphatase), increased bilirubin. Kidney function tests: increased blood creatinine and urea nitrogen

(BUN) levels (kidney damage). Fecal occult blood test: positive.

Дата добавления: 2015-06-25